Tutorial contains images and text for pathology education. Histology of the respiratory system consists of lungs and the passages that reach them nasal cavity,pharynx,trachea,bronchi and. Hepatocellular carcinoma hcc is the sixth most common type of cancer and with about 9. Histology cell biology thread university of virginia. Histology cell biology thread course subject areas all presentations. Fundus vesika billiaris berbentuk bulat dan biasanya menonjol di bawah permukaan margo inferior hepar, penonjolan ini. The liver is bounded by a connective tissue capsule which extends into its substance as highly branched septae. Histology image courtesy of education interactive human histology photo cd. Histology of the ear ear human head and neck scribd. Image modified from rohen and yokochi, color atlas of anatomy, igakushoin, 1988. The report has been cited more than 940 times since its publication. Pathology of liver and biliary tract, functions of the liver, hepatobiliary injury and responses, hepatic failure, hepatocutaneous syndrome, metabolic disturbances, potential mechanisms of hepatic lipidosis, causessyndromes of lipidosis, bacterial infections of the liver, parasitic diseases of liver, toxicinduced liver disease, diseases.
Embryologically it develops from the foregut and it spans the upper right and part of left abdominal quadrants. Anatomy anatomy the liver is the largest organ in the abdominal cavity and the most complex. Davern,7 victor navarro,8 rajender reddy,9 jayant a. Grading and staging the histopathological lesions of.
Ear the ear ear sensory organ functions as an auditory system for sound perception and as a vestibular system for balance. Hepatology is a branch of medicine concerned with the study, prevention, diagnosis and management of diseases that affect the liver, gallbladder, biliary tree. The cut surface of a normal liver has a brown color. Anatomi hepar free download as powerpoint presentation. Najeeb lectures are the worlds most popular medical lectures. Above this junction is the bile canaliculus into which the cells secrete bile from their apical surface. General structure external ear middle ear internal ear. At the periphery of the lobule is the portal triad consisting of a branch of the hepatic portal. Hepatology is a rapidly evolving medical field that will continue to grow and maintain our excitement over the next few decades. Microscopically, extrahepatic biliary atresia leads to this appearance in the liver, with numerous browngreen bile plugs, bile duct proliferation seen at lower center, and extensive fibrosis. Quicktime and a decompressor are needed to see this picture external ear pinna auricle elastic cartilage except in auricle lobule covered by hairbearing skin hair follicles, sweat gland and. The histopathologic features of chronic hepatitis from any cause are very similar and do not distinguish one disease from another. This site includes histology quizzes, histology games, slides, mnemonics, histology puzzles and tons of information about histology.
When looking at the histology it can be seen that the hepatocytes are arranged to form a liver lobule, which is the functional unit of the liver. Hepatology is a branch of medicine concerned with the study and management of diseases that affect the liver, gallbladder, biliary tree and pancreas. Anatomy secondlargest organ of the body and the largest gland, weighing about 11. Histology slide courtesy of corel professional photos histology cd. The spectrum of histologic findings in hepatic outflow. March 25, 2020 the liver is the largest internal organ of the human body, weighing approximately 1. Fusobacterium necrophorum corynebacterium pseudotuberculosis trueperella arcanobacterium pyogenes streptococci and staphylococci. Metabolic disturbances accumulations of fat glycogen amyloid copper pigments. Druginduced liver injury dili is an important cause of liver disease with significant morbidity and mortality.
If a large enough bile duct can be found to anastomose and provide bile drainage, then. Welldifferentiated hcc, however, may be difficult to distinguish from normal hepatic parenchyma or hepatocellular adenomas. Vesika billiaris mempunyai kemampuan menampung empedu sebanyak 3050 ml dan menyimpannya sera memekatkan empedu dengan cara mengabsorbsi air. Liver normal histology rifat mannan,md mount sinai st. Baixe no formato pdf, txt ou leia online no scribd. Talwalkar,10 andrew stolz,11 jiezhun gu,12 huiman barnhart,12 and jay h.
Lalu hepar diiris dan diberi pewarna tambahan safranino. At the center of the lobule is the central vein, which drains to the hepatic vein and is surrounded by numerous hepatocytes. Common indications include evaluating a liver before transplantation, assessing therapeutic response, diagnosing a mass lesion, and monitoring the hepatotoxicity of a drug regimen. Jaringan yang terdalam adalah kapsula renalis, jaringan pada lapisan kedua adalah adiposa, dan jaringan terluar adalah fascia renal. Viral hepatitis is not unlike hiv was 10 or 15 years ago when the retrovirus began to be better understood and treatable. Induction of innate immunity has little effect on hdv infection. Hepatitis b virus structure, epidemiology, symptoms, pathogenesis, diagnosis, treatment and vaccines. Histopathology images of hepatocellular carcinoma by. Serat kolagen jaringan ikat retikuler reticular connective tissue histology slide this is a histology slide of reticular connective tissue. Histopathology images of chronic hepatitis c by pathpedia. The extrahepatic pool of hcv is the major source of recurrent hepatitis c in orthotopic liver transplant. Liver anatomy and histology comparative pathology laboratory division of comparative medicine arlin rogers. Hepatocyte traf6 aggravates hsc activation in an ask1. Right, left, caudate, quadrate majority of liver on r side cranial abdomen subdivided into 9 discrete units based on.
The knodell histology activity index hai, published in hepatology in 1981,1 was the first system of its type and is widely regarded as the benchmark for objective, semiquantitative, reproducible description of the various morphological lesions of chronic hepatitis. The afferent blood vessels and lymphatics follow this connective tissue highway throughout the liver. In this section of rabbit liver, the lobules are not defined by a layer of connective tissue, as found for the pig. Nasal cavity proper respiratory mucosa olfactory mucosa. Pathology outlines hepatocellular carcinoma general. Near the hilum here, note the portal vein carrying blood to the liver, which branches at center left, with accompanying hepatic artery and bile ducts. Systematic evaluation and clinical associations david e.
Liver neoplasms are dealt with in the liver neoplasms article. Hepatic histological findings in suspected druginduced. Click on portal vein, hepatic artery, hepatic vein, and bile ducts in the liver below. Can you identify the portal tracts and central veins the liver has very little connective tissue, which explains its softness, and susceptibility to tearing in abdominal. Named after francis glisson 1599 1677 a british anatomist. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Histology of liver by aravindh dpi linkedin slideshare. A comprehensive, fun and entertaining site devoted exclusively to histology.
Plasma alt as a function of combined risk score, stratified by hsd17b rs726567 genotype. Free hepatology books download ebooks online textbooks. This arrangement is more typical for most mammals, including man. Histology of digestive system free download as powerpoint presentation. Temukan segala yang ditawarkan scribd, termasuk buku dan buku audio dari penerbitpenerbit terkemuka. Hepatocytes em this electron microscope shows two hepatocytes separated by their cell membranes. Hepatic lobules with central vein radiating hepatic cord cells portal triad 2. A junctional complex is located near the apical portion of these cells. The liver is designed to maintain bodys chemical and metabolic homeostasis. Liver histology, in conjunction with the full gamut of clinical and laboratory data, is considered to establish a diagnosis in multiple parenchymal liver diseases acute and chronic hepatitis, cholestatic disorders, fatty liver disease, vascular diseases, infiltrative or storage diseases, etc.
The liver is an organ pathologists are seeing less of, as radiologists with multimodal imaging and triphasic ct scans are pretty good at sortingout many types of liver lesions this article is an introduction to liver pathology. It is a major public health issue in the united states and worldwide. Not only does viral hepatitis carry a high morbidity, but it also stresses medical resources. Hepatitis c is an infectious hepatitis caused by hepatitis c virus hcv. Fundamental liver pathology part 1 duke university. Hepatitis b is a viral infection that attacks the liver and can cause both acute and chronic disease. Histology of the liver and gall bladder compatibility mode hanaa said. Untuk mempermudah deskripsinya vesika billiaris dibagi menjadi fundus,corpus dan collum. Introduction viral hepatitis, refers to infections that affect the liver and are caused by viruses. Hepatic histological findings in suspected druginduced liver injury. This is a section through the liver showing a classic hepatic lobule.
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